We wrote a review article covering the recent developments at the intersection of single-cell measurements, mammalian synthetic biology manipulations, and mathematical models of gene regulation.
PDF: Tycko & Van, 2017, Current Opinion in Biomedical Engineering
Here we review recent work that has taken promising initial steps towards the kind of quantitative, single-cell gene regulation framework that will enable us to understand, predict, and design gene regulatory systems in mammalian cells.
We had a great time diving into the literature and writing out our view of the field at this exciting moment. Enjoy this early look at what the Bintu lab is thinking about.
Our three new graduate students bring in diverse backgrounds and research skills:
Mike Van (Biology)
Josh Tycko (Genetics)
Sarah Lensch (Bioengineering)
Welcome to the lab everybody!
Lab BBQ with new students, rotation students, and significant others. This time we remembered to take a photo for the website 🙂
The incubators are shaking, the scope is imaging, the thermocyclers are cycling, the massive Goodsell poster of the cell is hung on the wall – we are all moved in!
Thank you to the formidable efforts of lab manager Rhonda DiGiusto and building manager Patrick Carlson to create our beautiful space.
We’re sharing the space with Possu Huang’s lab of protein engineers.
We are looking for graduate students and postdocs who are interested in mammalian synthetic biology, chromatin and gene regulation, and quantitative biology.
Graduate students, please apply through one of the graduate programs at Stanford: Bioengineering, Biophysics, or Biosciences. If you are at Stanford already, please email Lacra (lbintu at gmail) to chat about a potential rotation.
Postdocs, please email Lacra (lbintu at gmail).
The Bintu Lab is scheduled to start at Stanford in January of 2017.
Lab construction is still under way. Here are the lab plans, by the amazing Brian Carilli: